Kybella is the only FDA-approved injectable treatment for submental fullness (double chin). Kybella is a naturally occurring substance (deoxycholic acid) that targets and permanently destroys fat cells in the area where it is injected. Most patients need at least two treatments, spaced 6-8 weeks apart, to obtain noticeable improvement in their profile. The results of the treatment are permanent. Patients with loose skin or poor skin tone may not be suitable candidates for the procedure.